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Article

The inhibition of cyclin B1 gene transcription in quiescent NIH3T3 cells is mediated by an E-box.

Oncogene - 19 Sept 1996

Farina A, Gaetano C, Crescenzi M, Puccini F, Manni I, Sacchi A, Piaggio G

Abstract excerpt

Cyclin Bl plays an important role in cell proliferation. Its expression is tightly regulated at the mRNA and protein levels during the cell cycle and is found to be deregulated in various malignancies. To enlighten the signalling pathways which lead to the cell cycle dependent expression of the c...

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PMID: 8808703

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-8808703-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

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Research trail→

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The inhibition of cyclin B1 gene transcription in quiescent NIH3T3 cells is mediated by an E-box.PMID 8808703Read ↗

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Cyclin A Expression Is under Negative Transcriptional Control during the Cell CycleSemantic proximity Read ↗

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A novel transcriptional inhibitory element differentially regulates the cyclin D1 gene in senescent cells.Semantic proximity Read ↗

Circulating human B lymphocytes are deficient in nucleotide excision repair and accumulate mutations upon proliferation.Semantic proximity Read ↗

Cell cycle specific changes in the human cyclin B1 gene regulatory region as revealed by response to trichostatin A.Semantic proximity Read ↗

KLF4 is a FOXO target gene that suppresses B cell proliferationSemantic proximity Read ↗

Upstream Stimulatory Factor Regulates Expression of the Cell Cycle-Dependent Cyclin B1 Gene PromoterSemantic proximity Read ↗

CDC6 interacts with c-Myc to inhibit E-box-dependent transcription by abrogating c-Myc/Max complex.Semantic proximity Read ↗

Cyclin A repression in quiescent cells is associated with chromatin remodeling of its promoter and requires Brahma/SNF2alpha.Semantic proximity Read ↗

Loss of p21<sup>CDKN1A</sup>impairs entry to quiescence and activates a DNA damage response in normal fibroblasts induced to quiescenceSemantic proximity Read ↗

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