Article
Expression in human lung cancer cell lines of genes of prohormone processing and the neuroendocrine phenotype.
Journal of cellular biochemistry. Supplement - 1 Jan 1996
Vos M D, Scott F M, Iwai N, Treston A M
Abstract excerpt
Lung tumor cells and cell lines, principally the histologically classified small cell lung cancer, are characterized by the expression of neuroendocrine (NE) features including AADC (aromatic amino acid decarboxylase, previously called DOPA decarboxylase) and the production of many peptide hormon...
Topics
- Biomarkers, Tumor
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Small Cell
- Cell Differentiation
- Dopa Decarboxylase
- Enzyme Induction
- Gene Expression Regulation, Neoplastic
- Humans
- Lung Neoplasms
- Mixed Function Oxygenases
- Multienzyme Complexes
- Neoplasm Proteins
- Neuroendocrine Tumors
- Paraneoplastic Endocrine Syndromes
- Phenotype
- Protein Precursors
- RNA, Messenger
- Tumor Cells, Cultured