Article
Population haplotype analysis and evolutionary relations of the COL2A1 gene.
Annals of human genetics - 1 May 1996
Meulenbelt I, Williams C J, Te Koppele J M, Van de Giessen G C, Slagboom P E
Abstract excerpt
We have determined the allele frequencies and pairwise linkage disequilibria of restriction fragment length polymorphisms (RFLPs) distributed over the entire COL2A1 gene (spanning 23.6 kb) in a population of unrelated Dutch Caucasians. Pairwise linkage disequilibrium analysis of RFLP sites betwee...
Topics
- Collagen
- Evolution, Molecular
- Gene Frequency
- Genetic Linkage
- Genetics, Population
- Genotype
- Haplotypes
- Humans
- Linkage Disequilibrium
- Mutation
- Netherlands
- Osteoarthritis
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length
- White People