Article
Genetic structure and the search for genotype-phenotype relationships: an example from disequilibrium in the Apo B gene region.
Genetics - 1 Oct 1991
Zerba K E, Kessling A M, Davignon J, Sing C F
Abstract excerpt
We analyzed allelic associations (disequilibria) for four restriction fragment length polymorphisms (RFLPs) in the region of the 43-kb Apo B gene in a sample of 233 unrelated individuals from Montreal, Canada, sampled for health. This total sample (T) included 160 individuals of known French Canadian (FC) ancestry. We present a rigorous application of current methodology to these samples, including estimation of...
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