Genetic structure and the search for genotype-phenotype relationships: an example from disequilibrium in the Apo B gene region.

doi:10.1093/genetics/129.2.525

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Article

Genetic structure and the search for genotype-phenotype relationships: an example from disequilibrium in the Apo B gene region.

Genetics - 1 Oct 1991

Zerba K E, Kessling A M, Davignon J, Sing C F

Abstract excerpt

We analyzed allelic associations (disequilibria) for four restriction fragment length polymorphisms (RFLPs) in the region of the 43-kb Apo B gene in a sample of 233 unrelated individuals from Montreal, Canada, sampled for health. This total sample (T) included 160 individuals of known French Cana...

Topics

Adult
Apolipoproteins B
Canada
Female
Gene Frequency
Genetic Variation
Genotype
Humans
Linkage Disequilibrium
Male
Middle Aged
Phenotype
Polymorphism, Restriction Fragment Length

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