Article
Type 1 fimbrial expression enhances Escherichia coli virulence for the urinary tract.
Proceedings of the National Academy of Sciences of the United States of America - 3 Sept 1996
Connell I, Agace W, Klemm P, Schembri M, Mărild S, Svanborg C
Abstract excerpt
Type 1 fimbriae are adhesion organelles expressed by many Gram-negative bacteria. They facilitate adherence to mucosal surfaces and inflammatory cells in vitro, but their contribution to virulence has not been defined. This study presents evidence that type 1 fimbriae increase the virulence of Es...
Topics
- Animals
- Blotting, Southern
- Child
- DNA, Bacterial
- Escherichia coli
- Escherichia coli Infections
- Genotype
- Humans
- Mice
- Microscopy, Immunoelectron
- Nucleic Acid Hybridization
- Phenotype
- Pili, Sex
- Receptors, Immunologic
- Restriction Mapping
- Urinary Tract Infections