Article
Mechanical perturbation elicits a phenotypic difference between Dictyostelium wild-type cells and cytoskeletal mutants.
Biophysical journal - 1 Feb 1996
Eichinger L, Köppel B, Noegel A A, Schleicher M, Schliwa M, Weijer K, Witke W, Janmey P A
Abstract excerpt
To determine the specific contribution of cytoskeletal proteins to cellular viscoelasticity we performed rheological experiments with Dictyostelium discoideum wild-type cells (AX2) and mutant cells altered by homologous recombination to lack alpha-actinin (AHR), the ABP120 gelation factor (GHR), or both of these F-actin cross-linking proteins (AGHR). Oscillatory and steady flow measurements of Dictyostelium...
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