Article
Exotoxin A stimulates fluid reabsorption from distal airspaces of lung in anesthetized rats.
The American journal of physiology - 1 Feb 1996
Pittet J F, Hashimoto S, Pian M, McElroy M C, Nitenberg G, Wiener-Kronish J P
Abstract excerpt
To determine whether exotoxin A may affect the transport of fluid across the lung epithelium, two isogenic strains of Pseudomonas aeruginosa PA103 (10(8) colony-forming units), one (PA103 tox omega) with a structural gene mutation in exotoxin A, were instilled into the distal airspaces of anesthetized rats. PA103 parental strain, but not its mutant, stimulated the removal of fluid from the distal airspaces of the...
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