Article
The monoamine oxidase-A gene and major psychosis in Japanese subjects.
Biological psychiatry - 1 Nov 1998
Sasaki T, Hattori M, Sakai T, Kato T, Kunugi H, Hirose T, Nanko S
Abstract excerpt
BACKGROUND: Monoamine oxidase (MAO) is a critical enzyme in deamination of biogenic amines and may be involved in the pathophysiology of major psychosis, including mood disorder and schizophrenia. Recently, evidence for genetic association between the MAO-A gene and bipolar mood disorder was obtained in Caucasians. METHODS: We investigated the polymorphisms of the MAO-A gene, which may be related to enzyme...
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