Article
The monoamine oxidase-A gene and major psychosis in Japanese subjects.
Biological psychiatry - 1 Nov 1998
Sasaki T, Hattori M, Sakai T, Kato T, Kunugi H, Hirose T, Nanko S
Abstract excerpt
BACKGROUND: Monoamine oxidase (MAO) is a critical enzyme in deamination of biogenic amines and may be involved in the pathophysiology of major psychosis, including mood disorder and schizophrenia. Recently, evidence for genetic association between the MAO-A gene and bipolar mood disorder was obta...
Topics
- Adult
- Alleles
- Asian People
- Bipolar Disorder
- Case-Control Studies
- Chi-Square Distribution
- Depressive Disorder
- Female
- Genotype
- Humans
- Japan
- Male
- Middle Aged
- Monoamine Oxidase
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Psychotic Disorders
- Schizophrenia