Clinical application of genetic polymorphism in neurofibromatosis type 1.

Article

Clinical application of genetic polymorphism in neurofibromatosis type 1.

Annales de genetique - 1 Jan 1996

Clementi M, Boni S, Mammi I, Favarato M, Tenconi R

Abstract excerpt

The authors report the study of DNA polymorphic sequences, 5 intragenic and 5 flanking the NF1 gene, in 87 Italian NF1 families for a total of 142 affected individuals and 204 non-affected relatives. All PCR-based analyses are easy and simple to perform, and require small amounts of DNA. The non...

Topics

Female
Genes, Neurofibromatosis 1
Humans
Italy
Male
Mutation
Pedigree
Polymorphism, Genetic
Prenatal Diagnosis
Registries
Retrospective Studies

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