Down-regulation of paramyxovirus hemagglutinin-neuraminidase glycoprotein surface expression by a mutant fusion protein containing a retention signal for the endoplasmic reticulum.

doi:10.1128/JVI.70.8.5005-5015.1996

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Article

Down-regulation of paramyxovirus hemagglutinin-neuraminidase glycoprotein surface expression by a mutant fusion protein containing a retention signal for the endoplasmic reticulum.

Journal of virology - 1 Aug 1996

Tanaka Y, Heminway B R, Galinski M S

Abstract excerpt

The human parainfluenza virus type 3 (HPIV3) fusion (F) and hemagglutinin-neuraminidase (HN) glycoproteins are the principal components involved in virion receptor binding, membrane penetration, and ultimately, syncytium formation. While the requirement for both F and HN in this process has been...

Topics

Down-Regulation
Endoplasmic Reticulum
HN Protein
HeLa Cells
Humans
Mutation
Plasmids
Recombinant Fusion Proteins
Respirovirus
Viral Proteins

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