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Article

Transcriptional repression of the ovine follicle-stimulating hormone-beta gene by 17 beta-estradiol.

1 Aug 1996

Abstract excerpt

Direct transcriptional inhibition of the gene that encodes ovine FSH beta-subunit (oFSH beta) by 17 beta-estradiol (E2) has been previously demonstrated by our laboratory. To determine which cis-acting elements in the 5'-flanking region of this gene may be involved in E2 regulation, DNA constructs containing deletions of the 5'-end of the oFSH beta gene were fused to a luciferase reporter and tested in transient...

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Share to Estrogen and related hormone effects
Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 8754772
DOI: 10.1210/endo.137.8.8754772

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