Article
Genetic heterogeneity of M type 3 group A streptococci causing severe infections in Tayside, Scotland.
Journal of clinical microbiology - 1 Jan 1996
Upton M, Carter P E, Orange G, Pennington T H
Abstract excerpt
To explain the worldwide increase in the frequency of severe infections by group A streptococci, molecular techniques are increasingly being employed to evaluate the genetic relationships of strains. We used restriction endonuclease analysis, pulsed-field gel electrophoresis (PFGE), the PCR, ribotyping, and DNA sequence analysis in a study of 13 group A streptococci isolated from a cluster of cases of serious...
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