Article
Precocious loss of physiological sleep in a case of Creutzfeldt Jakob disease: a serial polygraphic study.
Sleep - 1 Dec 1995
Terzano M G, Parrino L, Pietrini V, Mancia D, Spaggiari M C, Rossi G, Tagliavini F
Abstract excerpt
Creutzfeldt-Jakob disease (CJD) is a prion-related subacute encephalopathy producing widespread neuronal degeneration and spongiform pathological changes, especially in the neocortex. Progressive dementia, motor signs and electroencephalographic (EEG) alterations characterize the full stage of the disease. A series of eight 24-hour polygraphic recordings were carried out in the last 3 months of life of a...
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