Article
HLA-B27 subtypes among the Chukotka Native groups.
Archivum immunologiae et therapiae experimentalis - 1 Jan 1995
Krylov M Y, Reveille J D, Alexeeva L I, Erdesz S, Arnett F C, Benevolenskaya L I
Abstract excerpt
The purpose of this study was to assess the relative frequency of the known HLA-B27 subtypes in HLA-B27 positive Chukotka natives, which have higher frequencies of HLA-B27 (to 40%) and spondyloarthropathies (to 2%) than the Russian Caucasian population. Using oligotyping of the polymerase-chain reaction amplified second and third exons of the HLA-B27 gene in 86 DNA samples from HLA-B27 positive individuals were...
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