Article
[Analysis of a genetic factor of metal allergy--polymorphism of HLA-DR, -DQ gene].
Kokubyo Gakkai zasshi. The Journal of the Stomatological Society, Japan - 1 Mar 1996
Saito K
Abstract excerpt
To reveal immunogenetic factors involved in the pathogenesis of metal allergy, 30 unrelated Japanese patients with histories of metal allergy were typed for HLA. They were confirmed by an unequivocal positive patch-test reaction to mercury, nickel or palladium. The HLA-DR and -DQ DNA were typed by using the polymerase chain reaction-sequence specific oligonucleotide probe (PCR-SSO) method. The frequency of each...
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