HLA-DQA1 and DQB1 loci in nickel allergy patients.

Abstract excerpt

Since an association has been reported between nickel allergy and HLA-DQA TaqI restriction fragment length polymorphism, we typed the DQA1 locus by a more precise method to confirm the association and characterize it better. Typing was extended to the DQB1 locus. The loci were typed using polymerase chain reaction and sequence-specific oligonucleotides. The DQA1 allele 0601 was slightly overrepresented among the...

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