Article
[The relationship between silicosis and the polymorphism of HLA-DRB1 *, DQB1 * genes].
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases - 1 Apr 2002
Yuan Baojun, Zhang Zhixin, Li Hongfen, Chang Yanhe, Liu Zhizhong, Zou Jimin, Li Wei, Shan Xiaoyan
Abstract excerpt
OBJECTIVE: To investigate the relation between the susceptibility to silicosis and the polymorphism of HLA-DRB1 *, DQB1 * genes in Chinese Hans. METHODS: HLA-DRB1 * and DQB1 * gene polymorphism were tested in 48 silicosis patients and 100 normal controls by using polymerase chain reaction of sequence-specific primers (PCR-SSP). RESULTS: The allele frequencies of DRB1 * 1401 and DQB1 * 05 in silicosis patients...
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