Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

KGF and EGF differentially regulate the phenotype of prostatic epithelial cells.

Growth regulation - 1 Mar 1996

Peehl D M, Wong S T, Rubin J S

Abstract excerpt

Previous studies indicate that keratinocyte growth factor (KGF) acts as a paracrine factor in the prostatic epithelium and epidermal growth factor (EGF) acts as an autocrine factor. In serum-free medium, KGF or EGF promoted similar growth of human prostatic epithelial cells. Response to two growth-inhibitory factors (suramin and transforming growth factor-beta), and expression of keratins and prostate-specific...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Division
Share to Cells, Cultured
Share to Clone Cells

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epithelial Cells

Share to Epithelium

Share to EGF gene

Share to Phenotype

Share to Recombinant Proteins

Source

Identifiers

PMID: 8717447

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

KGF and EGF differentially regulate the phenotype of prostatic epithelial cells.PMID 8717447Read ↗

Basic FGF, EGF, and PDGF modify TGFbeta-induction of smooth muscle cell phenotype in human prostatic stromal cells.Semantic proximity Read ↗

Keratin expression: a measure of phenotypic modulation of human prostatic epithelial cells by growth inhibitory factors.Semantic proximity Read ↗

Induction of smooth muscle cell phenotype in cultured human prostatic stromal cells.Semantic proximity Read ↗

Role of the stromal microenvironment in carcinogenesis of the prostateSemantic proximity Read ↗

The role of stroma in prostatic carcinogenesisSemantic proximity Read ↗

Modulation of phenotype of human prostatic stromal cells by transforming growth factor-betas.Semantic proximity Read ↗

Selective interactions between prostate fibroblast and epithelial cells in co-culture maintain the BPH phenotype.Semantic proximity Read ↗

Comparison of marker protein expression in benign prostatic hyperplasia in vivo and in vitro.Semantic proximity Read ↗

Constitutive expression of FGF2/bFGF in non-tumorigenic human prostatic epithelial cells results in the acquisition of a partial neoplastic phenotype.Semantic proximity Read ↗

Differential growth rates in stromal cultures of human prostate derived from patients of varying ages.Semantic proximity Read ↗

Characteristics of FGF-receptors expressed by stromal and epithelial cells cultured from normal and hyperplastic prostates.Semantic proximity Read ↗

Prostatic stromal cell phenotype is directly modulated by norepinephrine.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.