Selective interactions between prostate fibroblast and epithelial cells in co-culture maintain the BPH phenotype.

doi:10.1159/000030274

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Article

Selective interactions between prostate fibroblast and epithelial cells in co-culture maintain the BPH phenotype.

Urologia internationalis - 1 Oct 1998

Bayne C W, Ross M, Donnelly F, Chapman K, Buck C, Bollina P, Habib F K

Abstract excerpt

Paracrine interactions between primary cultured prostate epithelial cells and stromal fibroblasts were investigated in relation to morphology, growth, androgen sensitivity and secretory activities using co-cultures in which the two populations were separated by a microporous membrane. In this new...

Topics

Cell Communication
Cell Division
Cholestenone 5 alpha-Reductase
Coculture Techniques
Culture Media, Conditioned
Dihydrotestosterone
Epithelial Cells
Fibroblasts
Humans
Hydrogen-Ion Concentration
Immunoenzyme Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Keratins

Male

Microscopy, Electron

Oxidoreductases

Phenotype

Prostate

Prostate-Specific Antigen

Source

Open in PubMed

Identifiers

PMID: 9792974
DOI: 10.1159/000030274

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9792974-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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