Article
Selective interactions between prostate fibroblast and epithelial cells in co-culture maintain the BPH phenotype.
Urologia internationalis - 1 Oct 1998
Bayne C W, Ross M, Donnelly F, Chapman K, Buck C, Bollina P, Habib F K
Abstract excerpt
Paracrine interactions between primary cultured prostate epithelial cells and stromal fibroblasts were investigated in relation to morphology, growth, androgen sensitivity and secretory activities using co-cultures in which the two populations were separated by a microporous membrane. In this new model system, both cell types maintained several aspects of the differentiated phenotype including the capacity to...
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