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Article

Evidence that residues exposed on the three-fold channels have active roles in the mechanism of ferritin iron incorporation.

The Biochemical journal - 15 Jul 1996

Levi S, Santambrogio P, Corsi B, Cozzi A, Arosio P

Abstract excerpt

Iron is thought to enter the ferritin cavity via the three-fold channel, which is lined in its narrowest part by the residues Asp-131 and Glu-134. We describe here variants of human ferritins with active and inactive ferroxidase centres having Asp-131 and Glu-134 substituted with Ala and Ala or w...

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Identifiers

PMID: 8713073
DOI: 10.1042/bj3170467
PMCID: PMC1217510

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-8713073-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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