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Article

Expression and Characterization of Inactivating and Activating Mutations in the Human Ca2+-sensing Receptor

1 Aug 1996

Abstract excerpt

Nearly 30 mutations have been identified to date in the coding region of the extracellular calcium-sensing receptor (CaR) that are associated with inherited human hypo- and hypercalcemic disorders. To understand the mechanisms by which the mutations alter the function of the receptor may help to discern the structure-function relationships in terms of ligand-binding and G protein coupling. In the present studies,...

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Identifiers

PMID: 8702647
DOI: 10.1074/jbc.271.32.19537

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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