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Article

Retinoic acid induces cells cultured from oral squamous cell carcinomas to become anti-angiogenic.

The American journal of pathology - 1 Jul 1996

Lingen M W, Polverini P J, Bouck N P

Abstract excerpt

Retinoids have shown great promise as chemopreventive against the development of squamous cell carcinomas of the upper aerodigestive tract. However, the exact mechanism by which they block new tumors from arising is unknown. Here, we report that 13-cis- and all-trans-retinoic acid, used at clinically achievable doses of 10(-6) mol/L or less, can directly and specifically affect cell lines cultured from oral...

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Identifiers

PMID: 8686749
PMCID: PMC1865246

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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