Article
Androgen receptor gene mutations are rarely associated with isolated penile hypospadias.
The Journal of urology - 1 Aug 1996
Sutherland R W, Wiener J S, Hicks J P, Marcelli M, Gonzales E T, Roth D R, Lamb D J
Abstract excerpt
PURPOSE: Hypospadias has no known single etiology but it has been linked to androgen insensitivity caused by mutations of the androgen receptor gene. The purpose of this study was to search for such mutations in cases of various degrees of isolated hypospadias to determine whether such an association exists and, if so, with any particular anatomical subgroup. MATERIALS AND METHODS: Isolated deoxyribonucleic acid...
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