Screening by genomic linkage studies and mutation analysis of hereditary adenomatous polyposis coli: usefulness for clinical practice.

doi:10.1007/s002689900090

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Article

Screening by genomic linkage studies and mutation analysis of hereditary adenomatous polyposis coli: usefulness for clinical practice.

World journal of surgery - 1 Jun 1996

Karner-Hanusch J, Wolf B, Zehetmayer M, Wrba F, Roth E, Mannhalter C

Abstract excerpt

A heterogeneous group of patients suffering from adenomatous polyposis coli (APC) were evaluated by clinical and genetic investigations for the first time in Austria. The patients belonged to eight unrelated APC families. In six families several family members were affected with APC, and linkage...

Topics

Adenomatous Polyposis Coli
Adult
Base Sequence
DNA
Genetic Linkage
Genetic Testing
Genotype
Humans
Middle Aged
Molecular Sequence Data

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