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Article

Reoxidation of the NADPH produced by the pentose phosphate pathway is necessary for the utilization of glucose by Kluyveromyces lactis rag2 mutants.

FEBS letters - 27 May 1996

González Siso M I, Freire Picos M A, Cerdán M E

Abstract excerpt

Kluyveromyces lactis mutants defective in the glycolytic enzyme phosphoglucose isomerase are able to grow in glucose media and to produce ethanol, but they depend on a functional respiratory chain and do not grow in glucose-antimycin media. We postulate that this is due to the necessity of reoxidizing, in the mitochondria, the NADPH produced by the pentose phosphate pathway, which may be highly active in these...

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PMID: 8654569
DOI: 10.1016/0014-5793(96)00390-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Reoxidation of the NADPH produced by the pentose phosphate pathway is necessary for the utilization of glucose by Kluyveromyces lactis rag2 mutants.PMID 8654569Read ↗

Two mechanisms for oxidation of cytosolic NADPH by Kluyveromyces lactis mitochondria.Semantic proximity Read ↗

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The Rag4 glucose sensor is involved in the hypoxic induction of KlPDC1 gene expression in the yeast Kluyveromyces lactis.Semantic proximity Read ↗

Identification of the first fungal NADP-GAPDH from Kluyveromyces lactis.Semantic proximity Read ↗

RAG1 and RAG2: nuclear genes involved in the dependence/independence on mitochondrial respiratory function for growth on sugars.Semantic proximity Read ↗

RAG4 gene encodes a glucose sensor in Kluyveromyces lactis.Semantic proximity Read ↗

A NADP-glutamate dehydrogenase mutant of the petit-negative yeast Kluyveromyces lactis uses the glutamine synthetase-glutamate synthase pathway for glutamate biosynthesis.Semantic proximity Read ↗

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Characterization of the second external alternative dehydrogenase from mitochondria of the respiratory yeast Kluyveromyces lactis.Semantic proximity Read ↗

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