Linkage of an American pedigree with palmoplantar keratoderma and malignancy (palmoplantar ectodermal dysplasia type III) to 17q24. Literature survey and proposed updated classification of the keratodermas.

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Article

Linkage of an American pedigree with palmoplantar keratoderma and malignancy (palmoplantar ectodermal dysplasia type III) to 17q24. Literature survey and proposed updated classification of the keratodermas.

Archives of dermatology - 1 Jun 1996

Stevens H P, Kelsell D P, Bryant S P, Bishop D T, Spurr N K, Weissenbach J, Marger D, Marger R S, Leigh I M

Abstract excerpt

OBJECTIVES: To determine linkage in a pedigree with palmoplantar keratoderma (PPK) associated with squamous cell carcinoma of the esophagus. DESIGN: A large American pedigree was studied and the clinical phenotype was described. Linkage analysis was performed using genomic DNA from key individual...

Topics

Chromosomes, Human, Pair 17
Ectodermal Dysplasia
Female
Genetic Linkage
Humans
Keratoderma, Palmoplantar
Male
Neoplasms
Pedigree
Phenotype
United States

Source

Open in PubMed

Identifiers

PMID: 8651714

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8651714-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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