Article
Linkage of an American pedigree with palmoplantar keratoderma and malignancy (palmoplantar ectodermal dysplasia type III) to 17q24. Literature survey and proposed updated classification of the keratodermas.
Archives of dermatology - 1 Jun 1996
Stevens H P, Kelsell D P, Bryant S P, Bishop D T, Spurr N K, Weissenbach J, Marger D, Marger R S, Leigh I M
Abstract excerpt
OBJECTIVES: To determine linkage in a pedigree with palmoplantar keratoderma (PPK) associated with squamous cell carcinoma of the esophagus. DESIGN: A large American pedigree was studied and the clinical phenotype was described. Linkage analysis was performed using genomic DNA from key individuals. SETTING: A community-based family study. PATIENTS: The family pedigree was expanded from a single index case. MAIN...
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