Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical experience with preimplantation genetic diagnosis of cystic fibrosis (delta F508).

Prenatal diagnosis - 1 Feb 1996

Ao A, Ray P, Harper J, Lesko J, Paraschos T, Atkinson G, Soussis I, Taylor D, Handyside A, Hughes M, Winston R M

Abstract excerpt

Preimplantation genetic diagnosis (PGD) was attempted in 12 couples in whom both parents carry the common delta F508 deletion causing cystic fibrosis (CF). In vitro fertilization (IVF) was followed by cleavage stage biopsy on days 2 and 3 and removal of one or two cells for genetic analysis by nested polymerase chain reaction (PCR) and heteroduplex formation. A total of 18 cycles resulted in 137 normally...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biopsy
Share to Cystic Fibrosis
Share to Cystic Fibrosis Transmembrane Conductance Regulator

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Testing

Share to Infant, Newborn

Share to Mutation

Share to Polymerase Chain Reaction

Share to Pregnancy

Source

Identifiers

PMID: 8650124
DOI: 10.1002/(SICI)1097-0223(199602)16:2<137::AID-PD824>3.0.CO;2-H

Genes

PGD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical experience with preimplantation genetic diagnosis of cystic fibrosis (delta F508).PMID 8650124Read ↗

Birth of a Normal Girl after in Vitro Fertilization and Preimplantation Diagnostic Testing for Cystic FibrosisSemantic proximity Read ↗

Preimplantation genetic diagnosis for single gene disorders: experience with five single gene disorders.Semantic proximity Read ↗

Assessment of the reliability of single blastomere analysis for preimplantation diagnosis of the delta F508 deletion causing cystic fibrosis in clinical practice.Semantic proximity Read ↗

Preconception and preimplantation diagnosis for cystic fibrosis.Semantic proximity Read ↗

Preimplantation genetic diagnosis for cystic fibrosis: a case report.Semantic proximity Read ↗

Clinical experience with preimplantation genetic diagnosis and intracytoplasmic sperm injection.Semantic proximity Read ↗

Single intragenic microsatellite preimplantation genetic diagnosis for cystic fibrosis provides positive allele identification of all CFTR genotypes for informative couples.Semantic proximity Read ↗

[Twin birth after preimplantation diagnosis for cystic fibrosis].Semantic proximity Read ↗

Embryo implantation after biopsy of one or two cells from cleavage-stage embryos with a view to preimplantation genetic diagnosisSemantic proximity Read ↗

Improving clinical preimplantation genetic diagnosis for cystic fibrosis by duplex PCR using two polymorphic markers or one polymorphic marker in combination with the detection of the DeltaF508 mutation.Semantic proximity Read ↗

Clinical application of preimplantation genetic diagnosis for cystic fibrosis.Semantic proximity Read ↗

Multiplex PCR combining deltaF508 mutation and intragenic microsatellites of the CFTR gene for pre-implantation genetic diagnosis (PGD) of cystic fibrosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.