Article
Clinical experience with preimplantation genetic diagnosis and intracytoplasmic sperm injection.
Human reproduction (Oxford, England) - 1 Apr 1998
Liebaers I, Sermon K, Staessen C, Joris H, Lissens W, Van Assche E, Nagy P, Bonduelle M, Vandervorst M, Devroey P, Van Steirteghem A
Abstract excerpt
Preimplantation genetic diagnosis (PGD) is a novel procedure whose use may be considered to obtain a very early prenatal diagnosis for couples at risk for transmitting genetic diseases. Using the polymerase chain reaction (PCR) or fluorescence in-situ hybridization (FISH) the genotype or the sex of biopsied cleavage-stage embryos obtained after in-vitro fertilization can be determined and selected embryos can...
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