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Article

Studies of the expression of the Wiskott-Aldrich syndrome protein.

The Journal of clinical investigation - 1 Jun 1996

Stewart D M, Treiber-Held S, Kurman C C, Facchetti F, Notarangelo L D, Nelson D L

Abstract excerpt

The Wiskott-Aldrich syndrome (WAS) is an X-linked disorder characterized by thrombocytopenia, eczema, disorders in cell-mediated and humoral immunity, and a proclivity to lymphoproliferative disease. The gene responsible encodes a 53-kD proline-rich protein of unknown function (WASP). We produced a FLAG-WASP fusion protein that was used to immunize mice and produce mAbs against WASP. Using monoclonal anti-WASP in...

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Identifiers

PMID: 8647957
DOI: 10.1172/JCI118712
PMCID: PMC507350

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Source receipt: pubmed, retrieved 7 Sept 2026.

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