Article
Studies of the expression of the Wiskott-Aldrich syndrome protein.
The Journal of clinical investigation - 1 Jun 1996
Stewart D M, Treiber-Held S, Kurman C C, Facchetti F, Notarangelo L D, Nelson D L
Abstract excerpt
The Wiskott-Aldrich syndrome (WAS) is an X-linked disorder characterized by thrombocytopenia, eczema, disorders in cell-mediated and humoral immunity, and a proclivity to lymphoproliferative disease. The gene responsible encodes a 53-kD proline-rich protein of unknown function (WASP). We produced...
Topics
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal
- B-Lymphocytes
- Base Sequence
- Blood Platelets
- Blotting, Western
- Cell Line
- Cell Line, Transformed
- Child, Preschool
- Cloning, Molecular
- DNA Primers
- DNA, Complementary
- Humans
- Infant
- Mice
- Molecular Sequence Data
- Monocytes