Article
Gene screening of thyroxine-binding globulin (TBG) deficiencies in the Japanese: only two mutations account for TBG deficiencies in the Japanese.
The Journal of clinical endocrinology and metabolism - 1 Feb 1996
Inagaki A, Miura Y, Mori Y, Saito H, Seo H, Oiso Y
Abstract excerpt
T4-binding globulin (TBG) is the principal transport protein for thyroid hormone in the circulation. Twelve mutations in the human TBG gene have been reported, and the inheritance of those variant TBGs was shown to be X-chromosome linked. We previously reported a nucleotide deletion at the codon...
Topics
- Alleles
- Base Sequence
- Codon
- Female
- Gene Deletion
- Heterozygote
- Humans
- Japan
- Male
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Thyroxine-Binding Proteins