Differential effects of two hydrocephalus/MASA syndrome-related mutations on the homophilic binding and neuritogenic activities of the cell adhesion molecule L1.

doi:10.1074/jbc.271.12.6563

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Article

Differential effects of two hydrocephalus/MASA syndrome-related mutations on the homophilic binding and neuritogenic activities of the cell adhesion molecule L1.

The Journal of biological chemistry - 22 Mar 1996

Zhao X, Siu C H

Abstract excerpt

The cell adhesion molecule L1 plays an important role in neural development. We have previously demonstrated that the second immunoglobulin-like domain (Ig2) of L1 contains both homophilic binding and neuritogenic activities (Zhao, X., and Siu, C.-H. (1995) J. Biol. Chem. 270, 29413-29421). Recen...

Topics

Animals
Base Sequence
Binding Sites
CHO Cells
Cricetinae
DNA Primers
DNA, Complementary
Glutathione Transferase
Humans
Hydrocephalus
Leukocyte L1 Antigen Complex
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Neural Cell Adhesion Molecules

Neurites

Rats

Recombinant Fusion Proteins

Syndrome

Source

Open in PubMed

Identifiers

PMID: 8636066
DOI: 10.1074/jbc.271.12.6563

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8636066-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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