Article
Enhanced T lymphocyte expression of LFA-1, ICAM-1, and the TNF receptor family member OX40 in HgCl2-induced systemic autoimmunity.
Scandinavian journal of immunology - 1 May 1996
Roos A, Claessen N, Weening J J, Aten J
Abstract excerpt
Injection of mercuric chloride into Brown Norway (BN) rats induces a T lymphocyte-dependent autoimmune syndrome. In order to investigate whether modification of adhesion and costimulatory molecules on T lymphocytes may be involved in early T lymphocyte activation by HgCl2, the authors analysed ex...
Topics
- Animals
- Autoimmunity
- CD4-Positive T-Lymphocytes
- CD8-Positive T-Lymphocytes
- Female
- Intercellular Adhesion Molecule-1
- Leukocyte Common Antigens
- Lymphocyte Activation
- Lymphocyte Function-Associated Antigen-1
- Mercuric Chloride
- Phenotype
- Rats
- Rats, Inbred BN
- Receptors, OX40
- Receptors, Tumor Necrosis Factor
- T-Lymphocyte Subsets
- Tumor Necrosis Factor Receptor Superfamily, Member 7