Article
DNA damage: chemistry, repair, and mutagenic potential.
Regulatory toxicology and pharmacology : RTP - 1 Feb 1996
Singer B
Abstract excerpt
This paper is an overview on the chemical and biochemical effects of three different human carcinogens on DNA in vitro in terms of adducts, their effect on replication, in vitro and in vivo, and their repair by enzymes from human cells. The carcinogenic compounds chosen for specific discussion ar...
Topics
- Acetaldehyde
- Alkylating Agents
- Animals
- Base Sequence
- Benzene
- Benzoquinones
- Carcinogens
- DNA
- DNA Adducts
- DNA Damage
- DNA Repair
- Humans
- Molecular Sequence Data
- Mutation
- Nitrosourea Compounds
- Structure-Activity Relationship
- Vinyl Chloride