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Staphylococcus aureus Small Colony Variants Are Induced by the Endothelial Cell Intracellular Milieu

1 Mar 1996

Abstract excerpt

Recent studies have reported that Staphylococcus aureus small colony variants (SCVs) can cause highly persistent infections in humans and in cultured endothelial cells. To understand the process by which SCVs of S. aureus appear in subjects who have not received antibiotic treatment, bovine endothelial cells were coincubated with a wild S. aureus strain for 72 h in the presence of lysostaphin. Intracellular...

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PMID: 8627043
DOI: 10.1093/infdis/173.3.739

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