Cellular crossreactivity. Implications for solid organ transplantation matching.

doi:10.1097/00007890-199602270-00021

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Article

Cellular crossreactivity. Implications for solid organ transplantation matching.

Transplantation - 27 Feb 1996

Johnson A H, Araujo H, Tang T F, Lee K W, Steiner N, Hurley C K

Abstract excerpt

This study evaluates the cellular crossreactivity among DR11, DR13, and DR8 molecules using TLC reagents generated in reciprocal priming combinations where the responder and stimulator cells express different microvariants of DR11. The large majority of T lymphocyte clones (TLC) derived from such stimulation detect not only the product of the specific DR11 allele expressed by the stimulator but also detect...

Topics

Alleles
Animals
Clone Cells
Cross Reactions
Epitopes
HLA-DR Antigens
HLA-DR Serological Subtypes
Humans
Kidney Transplantation
Lymphocyte Activation
Mice
T-Lymphocytes
Transplantation Immunology

Source

Open in PubMed

Identifiers

PMID: 8610394
DOI: 10.1097/00007890-199602270-00021

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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