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Specific detection of hepatitis C virus minus strand RNA in hematopoietic cells.

1 Feb 1996

Abstract excerpt

The presence of hepatitis C virus (HCV) negative strand RNA in extrahepatic compartments based on PCR detection assays has been suggested in many reports with a very heterologous detection rate (from 0 to 100%). In this study, we have analyzed the presence of HCV negative strand in hepatic (liver biopsies, n = 20) and extrahepatic (sera, n = 32; PBMC, n = 26 and fresh bone marrow cells, n = 8) compartments from...

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PMID: 8609243
DOI: 10.1172/jci118485

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