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Article

Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene

1 Apr 1996

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 8606772
DOI: 10.1038/380528a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP genePMID 8606772Read ↗

Expression of truncated PrP targeted to Purkinje cells of PrP knockout mice causes Purkinje cell death and ataxia.Semantic proximity Read ↗

Purkinje cell death: Differences between developmental cell death and neurodegenerative death in mutant miceSemantic proximity Read ↗

Retinitis pigmentosa-associated mutations in mouse Prpf8 cause misexpression of circRNAs and degeneration of cerebellar granule cells.Semantic proximity Read ↗

Retinitis pigmentosa associated mutations in mouse Prpf8 cause misexpression of circRNAs and degeneration of cerebellar granule neuronsSemantic proximity Read ↗

Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions.Semantic proximity Read ↗

Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain.Semantic proximity Read ↗

Cerebellar defects in a mouse model of juvenile neuronal ceroid lipofuscinosisSemantic proximity Read ↗

129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal.Semantic proximity Read ↗

Hyperactivity of Purkinje cell and motor deficits in C9orf72 knockout miceSemantic proximity Read ↗

Hyperspiny Purkinje cell, a new neurological mutation in the mouse.Semantic proximity Read ↗

Identification of a novel gene encoding a PrP-like protein expressed as chimeric transcripts fused to PrP exon 1/2 in ataxic mouse line with a disrupted PrP gene.Semantic proximity Read ↗

A mouse prion protein transgene rescues mice deficient for the prion protein gene from purkinje cell degeneration and demyelination.Semantic proximity Read ↗

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