Article
Nonallelism of erd and prcd and exclusion of the canine RDS/peripherin gene as a candidate for both retinal degeneration loci.
Investigative ophthalmology & visual science - 1 Apr 1996
Ray K, Acland G M, Aguirre G D
Abstract excerpt
PURPOSE: To determine whether early retinal degeneration (erd) and progressive rod cone degeneration (prcd), two canine hereditary retinal degenerations, are caused by allelic mutations; to determine the cDNA sequence of the canine RDS/peripherin homolog (CFRDSP); and to test whether mutations(s) in CFRDSP cause(s) either erd or prcd. METHODS: Three erd-affected dogs were crossbred to three prcd-affected dogs,...
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