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Article

Method for Determining RNA 3' Ends and Application to Human Telomerase RNA

1 Feb 1996

Abstract excerpt

Mapping the 3′ ends of RNA molecules at nucleotide sequence resolution is a frequently encountered problem. S1 nuclease mapping ( 1 ) is a sensitive and often very successful approach for localizing 3′ ends, although it does not usually allow specification of an exact end with confidence. Enzymatic labeling of the 3′-terminus of an RNA followed by RNA sequencing is readily applicable to RNAs that can be obtained...

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Share to Advanced biosensing and bioanalysis techniques
Share to RNA Interference and Gene Delivery
Share to Telomeres, Telomerase, and Senescence

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PMID: 8602368
DOI: 10.1093/nar/24.3.532

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