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Article

Altered circadian activity rhythms and sleep in mice devoid of prion protein.

Nature - 18 Apr 1996

Tobler I, Gaus S E, Deboer T, Achermann P, Fischer M, Rülicke T, Moser M, Oesch B, McBride P A, Manson J C

Abstract excerpt

There is a wealth of data supporting a central role for the prion protein (PrP) in the neurodegenerative prion diseases of both humans and other species, yet the normal function of PrP, which is expressed at the cell surface of neurons and glial cells, is unknown. It has been speculated that neur...

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Identifiers

PMID: 8602267
DOI: 10.1038/380639a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-8602267-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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