Article
Opa-typing: a high-resolution tool for studying the epidemiology of gonorrhoea.
Molecular microbiology - 1 Sept 1995
O'Rourke M, Ison C A, Renton A M, Spratt B G
Abstract excerpt
A single gonococcus possesses a family of 11 distinct and highly variable opa genes. The extensive variation and rapid evolution of the opa gene repertoire has been exploited to provide a high-resolution typing method for studies of the short-term transmission of gonorrhoea. The 11 opa genes are...
Topics
- Antigens, Bacterial
- Bacterial Outer Membrane Proteins
- Base Sequence
- Chromosomes, Bacterial
- DNA Fingerprinting
- DNA Primers
- DNA, Bacterial
- Genes, Bacterial
- Genetic Variation
- Gonorrhea
- Humans
- Molecular Sequence Data
- Neisseria gonorrhoeae
- Polymerase Chain Reaction
- Reproducibility of Results