Article
Lethality of rep recB and rep recC double mutants of Escherichia coli.
Molecular microbiology - 1 Sept 1995
Uzest M, Ehrlich S D, Michel B
Abstract excerpt
A rep mutation in combination with a recB or a recC mutation renders Escherichia coli non-viable. This conclusion is based on the following lines of evidence: (i) double mutants cannot be constructed by P1 transduction; (ii) induction of the lambda Gam protein, which inactivates most of the RecBCD activities, is lethal in rep mutants; (iii) rep recBts recCts mutants are not viable at high temperature. The resons...
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