Article
sbcB sbcC null mutations allow RecF-mediated repair of arrested replication forks in rep recBC mutants.
Molecular microbiology - 1 Aug 1999
Bidnenko V, Seigneur M, Penel-Colin M, Bouton M F, Dusko Ehrlich S, Michel B
Abstract excerpt
We have proposed previously that, in Escherichia coli, blockage of replication forks can lead to the reversal of the fork. Annealing of the newly synthesized strands creates a double-stranded end adjacent to a Holliday junction. The junction is migrated away from the DNA end by RuvAB and can be cleaved by RuvC, while RecBCD is required for the repair of the double-stranded tail. Consequently, the rep mutant, in...
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