A tale of four syndromes: familial adenomatous polyposis, Gardner syndrome, attenuated APC and Turcot syndrome.

Article

A tale of four syndromes: familial adenomatous polyposis, Gardner syndrome, attenuated APC and Turcot syndrome.

QJM : monthly journal of the Association of Physicians - 1 Dec 1995

Foulkes W D

Abstract excerpt

Familial adenomatous polyposis (FAP), Gardner syndrome (polyposis, osteomas and epitheliomas), flat adenoma syndrome (attenuated APC) and Turcot syndrome (colorectal polyposis with brain tumours) are distinctive clinical syndromes. Each is caused by mutations in the adenomatous polyposis coli (AP...

Topics

Adenomatous Polyposis Coli
Base Sequence
Brain Neoplasms
Gardner Syndrome
Genes, APC
Genetic Linkage
Humans
Molecular Sequence Data
Mutation
Neoplasms, Multiple Primary
Neoplastic Syndromes, Hereditary
Pedigree
Phenotype

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.