Article
Increased microsatellite variability in Macaca mulatta compared to humans due to a large scale deletion/insertion event during primate evolution.
Electrophoresis - 1 Sept 1995
Kayser M, Nürnberg P, Bercovitch F, Nagy M, Roewer L
Abstract excerpt
Human (GATA)n microsatellites D12S66 and D12S67 could be successfully amplified by polymerase chain reaction (PCR) in various species of apes and monkeys. In 86 unrelated animals of the most intensively studied species Macaca mulatta we demonstrated five alleles at "D12D66" differing in size in i...
Topics
- Alleles
- Animals
- Base Sequence
- Biological Evolution
- Chromosome Deletion
- Genetic Variation
- Humans
- Macaca mulatta
- Microsatellite Repeats
- Molecular Sequence Data
- Mutagenesis, Insertional
- Primates
- Sequence Homology, Nucleic Acid
- Species Specificity
