Article
Human herpesvirus 6 variant A, but not variant B, infects EBV-positive B lymphoid cells, activating the latent EBV genome through a BZLF-1-dependent mechanism.
AIDS research and human retroviruses - 1 Oct 1995
Cuomo L, Angeloni A, Zompetta C, Cirone M, Calogero A, Frati L, Ragona G, Faggioni A
Abstract excerpt
Human herpesvirus 6, a predominantly T lymphotropic virus, has been recently shown to infect some EBV-positive B cell lines, and to induce in them the activation of the EBV lytic cycle. Here we have confirmed and extended such observations, showing that (1) this phenomenon is restricted to the va...
Topics
- B-Lymphocytes
- Cell Line
- DNA-Binding Proteins
- Genetic Variation
- Heating
- Herpesvirus 4, Human
- Herpesvirus 6, Human
- Humans
- Trans-Activators
- Ultraviolet Rays
- Viral Proteins