Article
Efficient propagation of human herpesvirus 6B in a T-cell line derived from a patient with adult T-cell leukemia/lymphoma.
Microbiology and immunology - 1 Jan 1999
Zhou C F, Abe K, Wang P, Ojima T, Yamamoto K
Abstract excerpt
The efficient propagation of the OK strain of the B variant of human herpesvirus 6 (HHV-6B) was demonstrated in a line of T cells, TaY, established from the peripheral blood lymphocytes of a patient with adult T-cell leukemia/lymphoma (ATL). Growth of TaY cells depends on the presence of IL-2 and the cells harbor HTLV-I genomes. A severe cytopathic effect (CPE) was observed in many HHV-6B(OK)-infected TaY cells...
Topics
- Antigens, CD
- Antigens, Differentiation, T-Lymphocyte
- Base Sequence
- Cytopathogenic Effect, Viral
- DNA Primers
- DNA Probes
- DNA, Viral
- Enzyme-Linked Immunosorbent Assay
- Genes, pX
- Genetic Variation
- Herpesvirus 6, Human
- Human T-lymphotropic virus 1
- Humans
- Leukemia-Lymphoma, Adult T-Cell