Haplotype analysis of French, British and other European patients with familial amyloid polyneuropathy (met 30 and tyr 77).

doi:10.1007/BF00866917

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Article

Haplotype analysis of French, British and other European patients with familial amyloid polyneuropathy (met 30 and tyr 77).

Journal of neurology - 1 Oct 1995

Reilly M M, Adams D, Davis M B, Said G, Harding A E

Abstract excerpt

Familial amyloid polyneuropathy (FAP) is an autosomal dominant disorder originally and most frequently described in Portugal. The usual constituent amyloid fibril protein is transthyretin (TTR) and the most frequent mutation in the TTR gene associated with FAP (including all Portuguese cases) is...

Topics

Amyloid Neuropathies
Base Sequence
Europe
France
Genes, Dominant
Haplotypes
Humans
Methionine
Molecular Sequence Data
Mutation
Polymorphism, Genetic
Tyrosine
United Kingdom

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