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Article

Protection against Papillomavirus with a Polynucleotide Vaccine

1 Feb 1996

Abstract excerpt

Genital infections with human papillomavirus (HPV) are increasingly recognized as a significant source of human disease; HPV is now implicated in up to 90% of cervical carcinomas. Neutralizing antibodies against papillomaviruses recognize conformational epitopes formed when viral capsid proteins assemble into virions or virus-like particles. Immunization with plasmid DNA encoding the major viral capsid protein L1...

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PMID: 8568291
DOI: 10.1093/infdis/173.2.314

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