Article
Protection of rabbits against challenge with rabbit papillomaviruses by immunization with the N terminus of human papillomavirus type 16 minor capsid antigen L2.
Journal of virology - 1 Nov 2007
Gambhira Ratish, Jagu Subhashini, Karanam Balasubramanyam, Gravitt Patti E, Culp Timothy D, Christensen Neil D, Roden Richard B S
Abstract excerpt
Current L1 virus-like particle (VLP) vaccines provide type-restricted protection against a small subset of the human papillomavirus (HPV) genotypes associated with cervical cancer, necessitating continued cytologic screening of vaccinees. Cervical cancer is most problematic in countries that lack the resources for screening or highly multivalent HPV VLP vaccines, suggesting the need for a low-cost, broadly...
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